Ro
From$149/mo
Source: Ro pricing page · Checked
Checked · confirm at checkout
Sesame is best for people seeking ongoing clinician care and FDA-approved brand options, but its low advertised care fee excludes medication and requires an annual commitment.
3.9/5
Source: Sesame official weight-loss program · Checked
Check this: Checked over 30 days ago.
Confirm the price at checkout.
The $59 headline is a care-only annual-plan equivalent, not the complete monthly treatment cost.
Medication prices can be substantially higher than the clinical subscription.
Compounded semaglutide is not currently available through Sesame, according to its official semaglutide page; this should be rechecked before enrollment but does not necessarily rule out every compounded product category unless confirmed directly by Sesame.
From$149/mo
Source: Ro pricing page · Checked
Checked · confirm at checkout
From$149/mo
Source: Hims weight loss page · Checked
Checked · confirm at checkout
From$199/mo
Source: TrimRx homepage · Checked
Checked · confirm at checkout
Educational content only. Do not use this page as medical advice or as a substitute for a licensed clinician, pharmacist or insurer reviewing your situation.
Sources: Sesame official weight-loss programSesame official semaglutide pageSesame Success program announcementSesame telehealth availability pageFDA Foundayo approvalFDA Wegovy tablet approval letterFDA Zepbound approvalChecked
From $59/mo
Source: Sesame official weight-loss programSesame is best for people seeking ongoing clinician care and FDA-approved brand options, but its low advertised care fee excludes medication and requires an annual commitment.
Last checked Jul 5, 2026
Price snapshot: From $59/mo
Sesame separates the care subscription from the prescription bill. Its official Success by Sesame page advertises the lowest care rate as $59 per month with an annual subscription. It lists the month-to-month plan at $99 and says that plan is billed every 28 days; three-, six-, and twelve-month commitments are billed in advance on their respective schedules. The page does not clearly print every plan's checkout total, so confirm the amount charged upfront. The subscription includes telehealth visits, unlimited provider messaging, ongoing clinical care, app tools, and eligible lab work, but not medication. Sesame says brand-name GLP-1 drugs start at $149 per month without insurance, while the actual pharmacy cost depends on product, dose, coverage, and savings-program eligibility. Providers can help with prior-authorization paperwork, but Sesame does not bill insurance for the care subscription itself. Also note a live-page inconsistency: a $199 introductory Wegovy or Ozempic injection offer remains displayed, but the same page says that promotion expired June 30, 2026. In July 2026, do not count that price as current unless Sesame or the dispensing pharmacy reconfirms it.
Sesame's current model is centered on FDA-approved brand products rather than an included compounded drug. The program page features Wegovy tablets and pens (semaglutide), Zepbound injection formats (tirzepatide), and Foundayo tablets (orforglipron). FDA sources confirm Wegovy, Zepbound, and Foundayo have approved weight-management indications for eligible patients. Sesame also lists Ozempic, and its wider FAQ names Mounjaro, Rybelsus, and Victoza among diabetes drugs that may be associated with weight loss. Those are not interchangeable with weight-loss approval: for example, current FDA labeling lists Ozempic for type 2 diabetes and related cardiovascular and kidney outcomes, not weight loss, so use for weight loss would be off-label. Sesame explicitly states that compounded semaglutide is not currently available through the platform. That is narrower than saying Sesame offers no compounded drug of any kind, so a reader should re-check the exact product and pharmacy rather than assume. FDA also emphasizes that compounded GLP-1 drugs are not FDA-approved and do not undergo premarket review for safety, effectiveness, or quality. No drug is guaranteed; the clinician decides whether any prescription is appropriate after evaluation.
Pricing ledger
These are the public pricing claims and checkout questions that decide whether the offer is actually comparable.
Monthly equivalent with an annual subscription; medication is excluded.
Full annual checkout charge and renewal dateThis cadence can result in approximately 13 charges per year.
Current checkout price and billing scheduleSeparate brand-medication charge; actual cost varies by drug, dose, coverage, and pharmacy.
Exact prescription price and savings eligibilityFDA-approved brand products for eligible weight-management patients; Sesame also lists Ozempic, which is not FDA-approved for weight loss.
Current formulary and prescribed indicationSource: Sesame official weight-loss program · Checked
Checked · confirm at checkout
The care pathway begins with a health-history and goals intake, followed by a video consultation with a Sesame provider selected by the patient. Sesame says the clinician reviews medical history, creates a treatment plan, and may order metabolic lab testing. If treatment is clinically appropriate, the provider can prescribe a weight-loss medication and route it for home delivery or to a preferred pharmacy. The subscription advertises follow-up visits, unlimited provider messaging, refill support, and app-based tracking for weight, diet, exercise, sleep, goals, and side effects. A Sesame announcement also describes weekly app check-ins that providers can review when monitoring progress and making adjustments. This is ongoing telehealth care, not a guaranteed prescription transaction: provider discretion, contraindications, insurance rules, and pharmacy availability can all affect what happens next. Sesame says Quest Diagnostics lab work is included except in Arizona, Hawaii, North Dakota, New Jersey, New York, Oklahoma, Rhode Island, South Dakota, and Wyoming, where lab fees are additional. Because providers on the marketplace may set different prices, confirm that the clinician chosen at checkout participates at the advertised subscription rate and clarify how often live follow-ups are expected.
The $59 headline is a care-only annual-plan equivalent, not the complete monthly treatment cost.
Before paying, verify four separate layers. First, confirm the care contract: the total charged today, commitment length, renewal date, whether the $59 figure requires one annual payment, and the cancellation and refund deadline. The month-to-month option renews every 28 days, which can mean thirteen charges in roughly a year. Second, confirm the prescription: exact brand, active ingredient, formulation, dose, FDA-approved indication, and whether any proposed use is off-label. Third, confirm fulfillment: dispensing pharmacy, cash price or insurance copay, prior-authorization status, manufacturer-program eligibility, shipping fees, refrigeration handling for injections, and the price after any introductory period. Sesame's expired $199 Wegovy/Ozempic terms show why a price tile alone is insufficient. Fourth, confirm location rules. Sesame says licensed telehealth providers are available across all 50 states, but its weight-program page does not publish a simple current state-by-state eligibility table. Provider licensure, pharmacy shipping, and Quest lab coverage still vary by location. Ask for the full expected first charge and ongoing recurring total in writing, and verify compounded-versus-brand status from the prescription label and dispensing pharmacy, not merely from the active ingredient name.
Sesame fits people who want a continuing relationship with a licensed telehealth clinician, the ability to choose a provider, ongoing video care and messaging, and access to multiple FDA-approved brand GLP-1 options. It may be especially attractive to someone with insurance coverage for the medication, or a self-pay patient willing to compare manufacturer and pharmacy programs separately. The $59 monthly equivalent can make the clinical-care layer look economical for a person comfortable with an annual commitment, and included Quest lab work adds value in most states. It is a weaker fit for someone seeking one predictable, all-inclusive monthly charge, because the medication is a second bill and may cost much more than the care subscription. It also does not currently fit someone specifically seeking compounded semaglutide, and it cannot promise that a clinician will prescribe a preferred drug or that insurance will approve it. People who dislike prepayment may prefer the $99 month-to-month option, but should account for its 28-day billing cycle. It is also less convenient in the nine listed states where Quest lab costs are excluded. Anyone needing in-person examination or more complex obesity care should confirm whether telehealth alone is appropriate before enrolling.
Side-by-side
Use this as a shortlist, not a final ranking. The right choice still depends on your quote, medication route, insurance result and follow-up needs. All comparison pages.
| Provider | Advertised cost | Medication path |
|---|---|---|
| SesameCurrent review · Score 3.9/5 | From $59/mo Source: Sesame official weight-loss program · Checked Checked · confirm at checkout | FDA-approved brand access |
| TrimRxScore 4.1/5 | From $199/mo Source: TrimRx homepage · Checked Checked · confirm at checkout | Compounded GLP-1 |
| Hims + HersScore 4.2/5 | From $149/mo meds + membership Source: Hims weight loss page · Checked Checked · confirm at checkout | FDA-approved brand paths |
| RoScore 4.3/5 | $39 first month; meds separate Source: Ro pricing page · Checked Checked · confirm at checkout | Brand GLP-1 + insurance support |
Educational content only. Do not use this page as medical advice or as a substitute for a licensed clinician, pharmacist or insurer reviewing your situation.
Sources
Current care pricing, separate medication charges, featured drugs, billing cadence, care model, lab exclusions, and promotion expiration.
States that compounded semaglutide is not currently available through Sesame.
Program inclusions, provider choice, clinical oversight, and weekly app check-ins.
Sesame's general statement that licensed healthcare providers are available in all 50 states.
Confirms FDA approval of Foundayo for long-term weight reduction in eligible adults.
Confirms approval of oral Wegovy for adult long-term weight reduction.
Confirms Zepbound's chronic weight-management approval.